Effects of platelet-rich plasma on pain and muscle strength in patients with knee osteoarthritis.
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RESULTS:
The PRP group showed a significant reduction in the WOMAC-pain and -total scores compared to normal saline group (p < 0.05). Although a significantly greater percentage of knee strength (extensor > flexor) was found in the PRP group during a longer follow-up period, PRP treatment resulted in insignificant differences in muscle strength compared to normal saline.
CONCLUSIONS:
PRP treatment significantly improves pain, stiffness, and disability in patients with knee OA compared to normal saline treatment. Additional strength training is recommended to enhance muscle strength recovery.